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lead to the growth and development of prostate cancer or if prostate cancer cases detected during therapy are coincidental to treatment
increase in hematocrit (hct) and hemoglobin (hb) levels in clinical trials of testosterone replacement confirms the decade-old known effects of testosterone on erythropoesis
long-term administration of 1% androgel (5, 7
5, or 10 g/d) for 36 months showed that hb and hct levels increased steadily until month 12 in a dose-dependent manner with the 10 g/d group attaining the highest. hb and hct concentrations
26 after 12 months there was no further increase in the levels
in the same study, 9% of men achieved hb levels above 18 g/dl or hct greater than 56% at some point during the study
in a 12-month study of 1% testim in hypogonadal men, mean hb and hct values remained within the normal range
4% of subjects showed an increased hematocrit beyond the acceptable range and were discontinued from the study
30 however, none of these. studies examined if the response profile was significantly different in younger and older men
there is concern about the possibility of inadvertent interpersonal transfer of testosterone gel
in men, the bioavailability of applied testosterone gel is limited to 10%–15%
upon application, testosterone penetrates the skin, with alcohol acting as a permeation enhancer
when applied to the skin, the alcohol evaporates quickly leaving significant amount of testosterone on the skin
hence, a large reservoir of testosterone is left on the skin with the potential to be transferred
59 unpublished studies from manufacturers indicate that both androgel and testim have the potential to raise testosterone levels in women after skin contact with treated men even hours after application
additionally with abdominal application of testim, wearing a shirt did not completely prevent the transfer of testosterone to the partner in spite of covering the area with a shirt
as of may 7th 2009, the us food

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different users to access switch online, even if they’re on different switch consoles
if you’ve been collecting my nintendo gold points, they can be used to purchase a switch online membership, according to this nintendo support page
this documentation also specifies that the points « cannot be used for auto-renewal
according to nintendo, you’ll be able to try switch online for seven days at no cost
photo: shaun lucas / tom’s guide
you need nintendo switch online to play games such as mario kart 8 deluxe, splatoon 2 and arms online
however, you can still play fortnite without the service
you’ll also need switch online to chat with your switch pals online
using a separate mobile app (more on that later)
additionally, nintendo switch online finally brings cloud saves to the switch, allowing you to back your saves up online « for most nintendo switch games, » according to nintendo
that could come in handy if you break your switch, or decide to buy a second one
switch online will also get you exclusive discounts, similar to what you’d see on xbox live gold or playstation plus
oh yeah, and there’s one more big thing
switch online will also get you access to a compilation of classic nes games dubbed « nes – nintendo switch online » (yes, that’s the actual name)
the service will include 20 games at launch, with more to be added over time
these retro titles will feature online functionality, including competitive and co-op play as well as the ability to virtually « pass the controller » to an online friend
here are the 20 games available at launch:
and here are some games coming soon:
if you’re dead set on playing switch online’s nes games, you can pick up a pair of switch-compatible nes controllers for $60
however, the controllers are exclusive to switch online members, and you can only purchase one per membership
switch online includes cloud save functionality, which allows you to back up your save files to the internet and keep them safe in the event something happens to your console
your game saves will back up to the cloud automatically as long as you’re online, so you won’t have to worry about manually uploading anything
as discovered by game informer, certain games, such as splatoon 2, dark souls remastered and nba 2k19 won’t support cloud save functionality
nintendo told the publication that this feature is disabled for multiplayer titles in which you could potentially cheat by manipulating your saves, but it’s still a bummer for folks who simply want to keep their data secure for those games
the nintendo switch online app is allows you to chat with your friends while playing splatoon 2, mario kart 8 deluxe, arms, mario tennis aces and the system’s classic nes library
it also offers game-specific services, such as the ability to check stats and order gear in splatoon 2
the app is still a bit barebones and cumbersome (you can’t message friends, and can only set up a chat session while playing one of the aforementioned games), but we’re eager to see how it evolves throughout switch online’s lifespan
what’s the price and release date for nintendo switch online?
will there be a free trial?
what does nintendo switch online get you?
which classic nes games are coming to switch online?
what about those nes controllers?
how do nintendo switch cloud saves work?
how does the switch mobile app work?
best nintendo switch games to play now
nintendo switch 2018 report card: a solid sophomore effort
ultimate: release date, roster, modes and
september 20, 2018
2:11 pm edt
last updated
september 20, 2018
2:23 pm edt
nintendo never hid the fact that it would eventually launch a service for its successful switch console that would see users interested in online play paying for the privilege
that service finally arrived this week
is it worth it? for many players, probably
but you’d also be justified if you felt a bit miffed by what nintendo is offering
paying for online service has been part and parcel to the xbox and playstation experiences for years, and microsoft and sony have made it worth the price not just by delivering smooth and reliable online play in countless games, but also by adding features and perks ranging from free modern games to community building social and party features
players get plenty for the $70 they spend annually on each service
the problem with nintendo switch online – does it seem strange to anyone else that nintendo has tied the name of its service to a specific device rather than its complete family of platforms? – is that it doesn’t add all that much
and it leaves out some key rudimentary features, to boot
in a nutshell, here’s what you get with your subscription:
all of this costs $5 per month, or just $25 per year
you can also get a family membership for up to eight account holders for $45 per year
you’ll note that it’s significantly cheaper than sony and microsoft’s offerings – which is a good thing, since it’s missing some features that many people who play online games might view as vital
the most notable absence is support for voice chat without a smartphone and special app
the inability to just plug a headset into your switch

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