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any negative reaction to testosterone, before starting this long-term mode of treatment
for more information on testosterone implants, see testosterone (testosterone implants)
testogel) contain 1% testosterone that is absorbed through the skin
the gel is applied to the skin on the abdomen, shoulder or arm on a daily basis
the standard dose is 5 g (50 mg testosterone),. although the dose may be increased to as much as 10 g daily in some men, while others will respond adequately to 2
care must be taken to ensure the gel does not come into contact with the skin of individuals other than the man being treated (e
sexual partners, children) for. at least six hours following application, as this may cause testosterone to be transferred to the contact’s skin and absorbed by their body
absorbing testosterone may be dangerous for children and women, especially pregnant women
for more information on testosterone gel, see testosterone (testogel)
andromen forte (testosterone) is a cream containing 5% testosterone
it is ideally applied to the skin of the scrotum on a daily basis
the cream can be applied to the skin of the torso, back, chest, arms and legs, although a higher dose might be required if these sites are used, as less testosterone is absorbed compared to if the cream. is applied to the scrotum
the usual starting dose is 1 g of cream (5 mg testosterone), but a doctor may adjust the dose depending on how the man responds

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market for home console gaming and eventually became the de facto industry standard
[84] announced in 1995, prior to the console’s 1996 launch, the 64dd (« dd » standing for « disk drive ») was designed to enable the development of new genre of video games[85] by way of 64 mb writable magnetic disks, video editing, and internet connectivity
eventually released only in japan in 1999, the 64dd peripheral’s commercial failure there resulted in only nine games being released and precluded further worldwide release
the gamecube (officially called nintendo gamecube, abbreviated ngc in japan and gcn in north america) was released in 2001, in japan and north america, and in 2002 worldwide
the sixth-generation console is the successor to the nintendo 64 and competed with sony’s playstation 2, microsoft’s xbox, and sega’s dreamcast
the gamecube is the first nintendo console to use optical discs as its primary storage medium
[86] the discs are similar to the minidvd format, but the system was not designed to play standard dvds or audio cds
nintendo introduced a variety of connectivity options for the gamecube
the gamecube’s game library has sparse support for internet gaming, a feature that requires the use of the aftermarket nintendo gamecube broadband adapter and modem adapter
the gamecube supports connectivity to the game boy advance, allowing players to access exclusive in-game features using the handheld as a second screen and controller
the wii was released during the holiday season of 2006 worldwide
the system features the wii remote controller, which can be used as a handheld pointing device and which detects movement in three dimensions
another notable feature of the console is wiiconnect24, which enables it to receive messages and updates over the internet while in standby mode
[87] it also features a game download service, called « virtual console », which features emulated games from past systems
since its release, the wii has spawned many peripheral devices, including the wii balance board and motion plus, and has had several hardware revisions
the wii family edition variant is identical to the original model, but is designed to sit horizontally and removes the gamecube compatibility
the wii mini is a smaller, redesigned wii which lacks gamecube compatibility, online connectivity, the sd card slot and wi-fi support, and has only one usb port unlike the previous models’ two
the wii u, the successor to the wii, was released during the holiday season of 2012 worldwide
[90][91] the wii u is the first nintendo console to support high-definition graphics
the wii u’s primary controller is the wii u gamepad, which features an embedded touchscreen
each game may be designed to use this touchscreen as supplemental to the main tv, or as the only screen for off-tv play
the system supports most wii controllers and accessories, and the more classically shaped wii u pro controller
[92] the system is backward compatible with wii software and accessories; this mode also utilises wii-based controllers, and it optionally offers the gamepad as its primary wii display and motion sensor bar
the console has various online services powered by nintendo network, including: the nintendo eshop for online distribution of software and content; and miiverse, a social network which can be variously integrated with games and applications
as of 31 march 2018, worldwide wii u sales had totalled over 13 million units, with over 100 million games and other software for it sold
on 17 march 2015, nintendo announced a new « dedicated games platform with a brand new concept » with the codename « nx » that would be further revealed in 2016
[49][51] reggie fils-aimé, president of nintendo of america, referred to nx as « our next home console » in a june 2015 interview with the wall street journal
[52] in a later article on 16 october 2015, the wall street journal relayed speculation from unnamed inside sources that, although the nx hardware specifications were unknown, it may be intended to feature « industry leading » hardware specifications and include both a console and a mobile unit that could either be used with the console or taken on the road for separate use
it was also reported that nintendo had begun distributing software development kits (sdks) for nx to third-party developers, with the unnamed source further speculating that these moves « [suggest that] the company is on track to introduce [nx] as early as [2016]
« [53] at an investor’s meeting on 27 april 2016, nintendo announced that the nx would be released worldwide in march 2017
[54] in an interview with asahi shimbun in may 2016, kimishima referred to the nx as « neither the successor to the wii u nor to the 3ds », as well as it being a « new way of playing games, » but it would « slow wii u sales » upon reveal and dissemination
[55] in june 2016, miyamoto stated that the reason nintendo had not released any information on the « nx » up until that point was because they were afraid of imitators, saying he and nintendo thought other companies could copy « an idea that [they’re] working on
« [94][95] the same day, kimishima revealed during a q&a session with investors that they were also researching virtual reality
[57] on 19 october 2016, nintendo announced they would release a trailer for the console the following day
[96] the next day, nintendo unveiled the trailer that

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